trans-Pralsetinib

SKU: orb1710042

Description

trans-Pralsetinib (BLU-667) is a potent and selective small molecule inhibitor targeting RET (Rearranged during Transfection) kinase. It is utilized in biochemical and cellular assays for oncology research, demonstrating activity in both in vitro studies and in vivo models of RET-altered cancers.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2097132-93-7
• MW: 533.6
• Formula: C₂₇H₃₂FN₉O₂
• SMILES: C(N[C@@H](C)C=1C=CC(=NC1)N2N=CC(F)=C2)(=O)[C@]3(OC)CC[C@@H](CC3)C=4N=C(NC5=NNC(C)=C5)C=C(C)N4
• Target: c-RET

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129073603