trans-Ned 19

SKU: orb1709033

Description

trans-Ned 19 is a pharmacological inhibitor that antagonizes NAADP receptors and blocks two-pore channels (TPCs). It is used in research to suppress intracellular calcium signaling, as demonstrated by its inhibition of calcium signals in HUVECs and histamine-induced vasodilation in isolated rat aorta.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1354235-96-3
• MW: 514.59
• Purity: 99.87% (May vary between batches)
• Formula: C₃₀H₃₁FN₄O₃
• SMILES: C(O)(=O)[C@@H]1CC2=C([C@H](N1)C3=CC(CN4CCN(CC4)C5=C(F)C=CC=C5)=C(OC)C=C3)NC=6C2=CC=CC6
• Target: Calcium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1427628