Trametiglue

SKU: orb1982314

Description

Trametiglue is a potent and selective Trametinib derivative that uniquely inhibits KSR-MEK and RAF-MEK interactions via interfacial binding. This makes it a valuable chemical probe for investigating RAS/MAPK pathway signaling in cancer research, applicable in both cellular and biochemical studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2666940-97-0
• MW: 666.46
• Formula: C₂₅H₂₄FIN₆O₅S
• SMILES: CC1=C2C(=C(NC3=C(F)C=C(I)C=C3)N(C)C1=O)C(=O)N(C(=O)N2C4=CC(NS(NC)(=O)=O)=CC=C4)C5CC5
• Target: Others,MEK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154700547