TRAF-STOP inhibitor 6877002

SKU: orb1706517

Description

TRAF-STOP inhibitor 6877002 is a selective small molecule that disrupts the CD40-TRAF6 interaction. It has been shown in research to attenuate macrophage activation and proliferation in atherosclerotic plaques, as well as reduce leukocyte recruitment in relevant in vivo models of inflammation.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 433249-94-6
• MW: 251.32
• Purity: 99.76%
• Formula: C₁₇H₁₇NO
• SMILES: Cc1ccc(C)c(N\C=C\C(=O)c2ccccc2)c1
• Target: NF-κB,TNF
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.92 mM);DMSO:112.5 mg/mL (447.64 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

TRAF-STOP inhibitor 6877002, NF-kB, NFkB, NFκB, NF-κB, CD40-TRAF6 inhibitor, CD40-TRAF6 interaction

Compound Identifiers

PubChem CID

2291556