TPBM

SKU: orb1689205

Description

TPBM is a potent and selective inhibitor of estrogen receptor α (ERα), with an IC₅₀ of 9 μM against E2-ERα binding and 5 μM in E2-dependent cell proliferation assays. It effectively blocks ERα recruitment to target genes and is useful for studying ERα function in breast cancer models, both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 6466-43-9
• MW: 316.38
• Purity: 99.64% (May vary between batches)
• Formula: C₁₅H₁₆N₄O₂S
• SMILES: O=C1C=2NC(=NC2N(C(=O)N1C)C)CSCC=3C=CC=CC3
• Target: Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

262425