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TP-353

SKU: orb1305921

Description

TP-353 (EOS-61973) is a potent and selective small molecule inhibitor of cyclin-dependent kinase 7 (CDK7). It is a valuable research tool for investigating transcriptional regulation, cell cycle progression, and oncology, with utility in both in vitro biochemical assays and in vivo cancer model studies.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1253799-29-9
MW531.62
Purity99.98%
FormulaC35H30FNO3
SMILESCc1c(F)cc(N(Cc2ccccc2)Cc2ccccc2)c(OCc2ccccc2)c1C(=O)Oc1ccccc1
TargetCDK
SolubilityDMSO:30 mg/mL (56.43 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CDK7, EOS 61973, EOS61973, EOS-61973, TP 353, TP353, TP-353

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

TP-353 (orb1305921)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 160.00
10 mg
$ 180.00
25 mg
$ 300.00
50 mg
$ 390.00
100 mg
$ 530.00
200 mg
$ 710.00
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