Tos-PEG4-t-butyl ester

SKU: orb1909254

Description

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a key PEG-based linker used in constructing PROTAC molecules for targeted protein degradation research. It has been utilized in the development of potent degraders like the FAK-targeting PROTAC BI-3663, which demonstrates nanomolar cellular activity in vitro.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 217817-01-1
• MW: 432.528
• Formula: C₂₀H₃₂O₈S
• SMILES: CC1=CC=C(S(=O)(OCCOCCOCCOCCC(OC(C)(C)C)=O)=O)C=C1
• Target: PROTAC Linker,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

60146205