Torezolid

SKU: orb1223843

Description

Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.(In Vitro):Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.(In Vivo):For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

Key Properties

• CAS Number: 856866-72-3
• MW: 370.34
• Purity: >98% (HPLC)
• Formula: C₁₇H₁₅FN₆O₃
• SMILES: O=C1O[C@@H](CO)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2
• Target: MAO
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TR-701 | tedizolid

Quick Database Links

Gene Symbol

MAO