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Topoisomerase inhibitor 6

SKU: orb3135511

Description

Topoisomerase inhibitor6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV, with an MIC of 0.06 μg/mL against fluoroquinolone-resistant S. aureus. It halts the DNA strand breaking-rejoining process, causing lethal DNA damage, and holds potential for studying infections caused by Gram-positive bacteria such as S. aureus and S. pneumoniae.

Research Area

Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2987726-03-2
MW404.87
FormulaC20H22ClFN4O2
SMILESClC1=C2C(C3=C(C(=O)N2C4CC4)N=C(C)O3)=CC(F)=C1N5C[C@]([C@H](C)N)(CC5)[H]
TargetAntibacterial,Topoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information