Topoisomerase I/II inhibitor 6

SKU: orb2695273

Description

This small molecule, known as Topoisomerase I/II inhibitor 6 (compound 3i), is a dual inhibitor of topoisomerase I (IC50 = 4.77 µM) and II (IC50 = 15 µM). It demonstrates antiproliferative activity in vitro against the LOX IMVI human melanoma cell line, with IC50 values of 26.7 µM and 25.4 µM, supporting its use in cancer research.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• MW: 622.64
• Formula: C₃₁H₂₈F₂N₄O₆S
• SMILES: O=C(NC1CCC(NC2=CC=CC=3C=NC=CC32)CC1)CCCCC4SSCC4
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139297409