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Topoisomerase II inhibitor 7

SKU: orb1745090

Description

This small molecule is a potent and selective inhibitor of topoisomerase II alpha (TOP2A) with an IC50 of 3.19 µM. It is a valuable research tool for studying DNA replication and repair, effectively inducing cell cycle arrest and apoptosis in vitro, and has been utilized in cancer research models.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2697171-03-0
MW674.56
FormulaC32H28BrN5O5S
SMILESC(OCC)(=O)C=1C(N2C=3C(SC2=NC1C4=CC=CC=C4)=C(N=C(N)N3)C5=CC=C(Br)C=C5)C6=CC(OC)=C(OC)C(OC)=C6
TargetOthers,Topoisomerase,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information