Topobexin

SKU: orb3135620

Description

Topobexin (Topobexin 9) is a highly selective TOP2B inhibitor. It selectively inhibits TOP2B in vitro and stabilizes TOP2B on DNA. Topobexin offers significant protection to cardiomyocytes against DAU-induced damage. In rabbit models, Topobexin prevents anthracycline-induced cardiotoxicity and the decrease in left ventricular contractile function caused by DAU.

Research Area

Molecular Biology

Key Properties

• CAS Number: 3076446-44-8
• MW: 489.61
• Formula: C₂₉H₃₅N₃O₄
• SMILES: O=C1OC2=C(C=CC(OCCN3CCN(C)CC3)=C2C(=O)N4C=5C=CC=CC5CCC4)C(=C1)CCC
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Topoisomerase