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Topiroxostat

SKU: orb1305544

Description

Topiroxostat (FYX-051) is a potent and selective xanthine oxidase inhibitor used in research on hyperuricemia and gout. It has demonstrated efficacy in both in vitro enzymatic assays and in vivo animal models, effectively lowering serum urate levels.

Research Area

Immunology & Inflammation, Metabolism Research

Images & Validation

Key Properties

CAS Number577778-58-6
MW248.24
Purity99.28% (May vary between batches)
FormulaC13H8N6
SMILESN#Cc1cc(ccn1)-c1nc(n[nH]1)-c1ccncc1
TargetROS,Cytochromes P450,Xanthine Oxidase
SolubilityDMSO:11 mg/mL (44.31 mM)

Bioactivity

Target IC50
XOR:5.3 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CYP3A4, CYPs, Cytochrome P450, Asn 768, acid, inhibit, Inhibitor, hyperuricemia, FYX 051, FYX051, FYX-051, XOR, XO, XanthineOxidase, Xanthine Oxidase, pharmacokinetic, Topiroxostat, uric

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Key Properties

No computed properties available.

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Topiroxostat (orb1305544)

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% DMSO +
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% Tween 80 +
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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
25 mg
$ 80.00
50 mg
$ 100.00
100 mg
$ 150.00
200 mg
$ 170.00
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