Topiroxostat

SKU: orb1305544

Description

Topiroxostat (FYX-051) is a potent and selective xanthine oxidase inhibitor used in research on hyperuricemia and gout. It has demonstrated efficacy in both in vitro enzymatic assays and in vivo animal models, effectively lowering serum urate levels.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 577778-58-6
• MW: 248.24
• Purity: 98.95% (May vary between batches)
• Formula: C₁₃H₈N₆
• SMILES: N#Cc1cc(ccn1)-c1nc(n[nH]1)-c1ccncc1
• Target: Xanthine Oxidase|||Cytochromes P450|||ROS
• Solubility: DMSO:11 mg/mL (44.31 mM)

Bioactivity

• Target IC50:
  XOR:5.3 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CYP3A4, CYPs, Cytochrome P450, Asn 768, acid, inhibit, Inhibitor, hyperuricemia, FYX 051, FYX051, FYX-051, XOR, XO, XanthineOxidase, Xanthine Oxidase, pharmacokinetic, Topiroxostat, uric

Compound Identifiers

PubChem CID

5288320