Topilutamide

SKU: orb1308998

Description

Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen used in research to study androgen receptor signaling. It has demonstrated efficacy in preclinical models for androgen-dependent conditions like acne and androgenic alopecia, through both in vitro and in vivo experiments.

Research Area

Metabolism Research

Key Properties

• CAS Number: 260980-89-0
• MW: 403.23
• Purity: 99.93% (May vary between batches)
• Formula: C₁₃H₁₁F₆N₃O₅
• SMILES: CC(O)(CNC(=O)C(F)(F)F)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
• Target: Androgen Receptor,Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.4 mM);DMSO:255 mg/mL (632.39 mM)

Bioactivity

• In Vivo:
  One of the commonly used approaches to treat metastatic prostate cancer is via first-generation nonsteroidal anti-androgens (NSAAs), namely Flutamide, Nilutamide, Bicalutamide and Topilutamide.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BP766, BP-766, BP 766, inhibit, Inhibitor, Fluridil, Topilutamide

Compound Identifiers

PubChem CID

9930988