Top1/2-IN-1

SKU: orb2665308

Description

Top1/2-IN-1 (Compound 23) is an orally active dual topoisomerase I/II inhibitor. It exerts antiproliferative effects in vitro by inducing DNA damage, ROS elevation, cell cycle arrest, and apoptosis. The compound has also demonstrated in vivo antitumor efficacy in xenograft mouse models.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• MW: 347.41
• Formula: C₂₁H₂₁N₃O₂
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Topoisomerase