Tonantzitlolone

SKU: orb1740898

Description

Tonantzitlolone is a natural small molecule that activates TRPC1/4/5 channels and PKCα/θ, inducing insulin resistance by suppressing IRS1 and the PI3K/Akt pathway. It also activates HSF1, promoting a glucose-dependent phenotype, making it a useful research tool for studying metabolism, cellular stress, and diabetes-related mechanisms in vitro.

Key Properties

• CAS Number: 845811-30-5
• MW: 464.59
• Formula: C₂₆H₄₀O₇
• SMILES: O[C@@]12[C@H](OC(/C=C(/CC)\C)=O)[C@H](C)C[C@@](O1)(C(=O)[C@@H](C)/C=C/C(C)(C)[C@]3(O[C@@](C)([C@@H]2O)CC3)[H])[H]
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25053359