Tolnaftate

SKU: orb1309795

Description

Tolnaftate (NP-27) is a synthetic thiocarbamate antifungal agent used in research. It is widely applied in vitro to study its mechanism against dermatophytes and in vivo models for topical treatment of fungal skin infections like tinea pedis.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2398-96-1
• MW: 307.41
• Purity: 98.85% (May vary between batches)
• Formula: C₁₉H₁₇NOS
• SMILES: O(C(N(C)C1=CC(C)=CC=C1)=S)C2=CC3=C(C=C2)C=CC=C3
• Target: Antifungal,Hedgehog/Smoothened
• Solubility: DMSO:65 mg/mL (211.44 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (8.13 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tolnaftate, Tonoftal, Sporiline, Smoothened, Tinactin, Fungal, Hedgehog, Inhibitor, inhibit, NP27, NP-27, NP 27

Compound Identifiers

PubChem CID

5510