Tolfenamic Acid

SKU: orb1310296

Description

Tolfenamic Acid (GEA 6414) is a fenamate NSAID used for migraine relief. It is employed in research to study cyclooxygenase (COX) inhibition and its anti-inflammatory and pro-apoptotic effects, with applications in both in vitro cellular assays and in vivo animal models.

Research Area

Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 13710-19-5
• MW: 261.70
• Purity: 99.71%
• Formula: C₁₄H₁₂ClNO₂
• SMILES: N(C1=C(C(O)=O)C=CC=C1)C2=C(C)C(Cl)=CC=C2
• Target: COX
• Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (7.64 mM);DMSO:49 mg/mL (187.24 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• Target IC50:
  COX-2:0.2 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Tolfedine, Tolfenamic Acid, inhibit, Inhibitor, GEA 6414, GEA6414, GEA-6414, COX, COX-2, Cyclooxygenase

Compound Identifiers

PubChem CID

610479