TNIK-IN-7

SKU: orb1944740

Description

TNIK-IN-7 is a potent and selective TNIK inhibitor (IC50: 11 nM) used to study colorectal cancer signaling. It demonstrates anti-proliferative effects in vitro and has shown efficacy in reducing tumor growth in preclinical in vivo models, supporting its role as a valuable research tool in oncology.

Research Area

Neuroscience, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1417795-24-4
• MW: 386.45
• Purity: 99.97% (May vary between batches)
• Formula: C₂₃H₂₂N₄O₂
• SMILES: N#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C=C3)N4CCOCC4
• Target: Others,Wnt/beta-catenin,Serine Protease
• Solubility: DMSO:7.14 mg/mL (18.48 mM)

Bioactivity

• Target IC50:
  TNIK:11 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TNIK, TNIKIN7, Wnt, Wnt/β-catenin, Wnt/b-catenin, Wnt/betacatenin, βcatenin, bcatenin, beta-catenin, betacatenin

Compound Identifiers

PubChem CID

71540728