TMX-3013

SKU: orb2802542

Description

TMX-3013 is a potent multi-CDK inhibitor with low nM IC50 values against CDK1, CDK2, CDK4, CDK5, and CDK6. It serves as a warhead for synthesizing CRBN-directed PROTAC degraders using a PEG linker, facilitating research into cell cycle regulation and targeted protein degradation in cancer models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2488761-18-6
• MW: 481.3
• Formula: C₁₇H₁₄BrFN₆O₃S
• SMILES: O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)S(=O)(=O)N
• Target: CDK,JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155184510