TMU 35435

SKU: orb2665448

Description

TMU 35435 is a histone deacetylase (HDAC) inhibitor that radiosensitizes triple-negative breast cancer (TNBC) cells. It functions by promoting proteotoxic stress, autophagy, and inhibiting DNA-PKcs via ubiquitination to impair non-homologous end joining (NHEJ) DNA repair, as demonstrated in vitro.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2231800-32-9
• MW: 379.45
• Formula: C₂₂H₂₅N₃O₃
• SMILES: O=C(NCCCCCCC(=O)NO)C1=CC=CC=2C=C3C=CC=C(C3=NC21)C
• Target: Autophagy,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638553