TMP780

SKU: orb1708348

Description

TMP780 is a potent inverse agonist of the nuclear receptor RORγt, exhibiting an IC50 of 13 nM. This small molecule is a valuable research tool for investigating RORγt's role in immunology and for preclinical studies in models of cutaneous inflammation, such as psoriasis.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1422053-03-9
• MW: 494.58
• Formula: C₃₁H₃₀N₂O₄
• SMILES: Cc1noc(C)c1[C@@H](O)c1cc2cc(CC(=O)N[C@@H](c3ccccc3)c3ccc(C)cc3C)ccc2o1
• Target: ROR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145925629