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TMP-269

SKU: orb1226564

Description

A potent and selective class IIa HDAC inhibitor with IC50s of 126/80/36/19 nM for HDAC4/5/7/9; less potent or no inhibition for others HDAC isoforms (>2 uM); prevents cell cycle progression, DNA synthesis, and proliferation induced in response to G protein-coupled receptor/PKD1 activation in IEC-18 cells.

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Key Properties

CAS Number1314890-29-3
MW514.5195
Purity>98% (HPLC)
FormulaC25H21F3N4O3S
SMILESO=C(NCC1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1)C4=CC=CC(C5=NOC(C(F)(F)F)=N5)=C4
TargetHDAC
SolubilityDMSO: ≥ 41 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TMP 269 | TMP269

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Protocol Information

TMP-269 (orb1226564)

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Available Sizes

Select a size below

2 mg
$ 110.00
5 mg
$ 150.00
10 mg
$ 220.00
25 mg
$ 350.00
50 mg
$ 610.00
100 mg
$ 720.00
200 mg
$ 1,030.00
500 mg
$ 1,530.00