TMC647055 Choline Hydroxide Salt

SKU: orb1306307

Description

TMC647055 Choline Hydroxide Salt is a potent non-nucleoside HCV NS5B polymerase inhibitor with nanomolar cellular antiviral activity (EC50 = 82 nM) and low cytotoxicity. Its promising preclinical pharmacokinetic profile in animal models supports its ongoing clinical evaluation for hepatitis C virus infection research.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• Target: HCV Protease
• Molecular Weight: 727.91
• Purity: 99.44% (May vary between batches)
• Formula: C₃₇H₅₃N₅O₈S
• SMILES: CN(CCOCCN1C)C(C2=CC3=C(C=CC(OC)=C3)C4=C(C5CCCCC5)C(C=CC(/C(O)=N/S1(=O)=O)=C6)=C6N4C2)=O.OCC[N+](C)(C)C.[OH-]

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1204416-97-6, 1204416-97-6 free base, HCVProtease, HCV Protease, HCV NS5B polymerase, TMC647055 Choline Hydroxide Salt, TMC-647055 Choline Hydroxide Salt, TMC647055 Choline Hydroxide Salt (1204416-97-6 free base)

Compound Identifiers

PubChem CID

118704751