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TMC-649128 PM

SKU: orb1741413

Description

TMC-649128 PM is a potent nucleoside inhibitor targeting the HCV NS5B RNA-dependent RNA polymerase, exhibiting an in vitro EC₅₀ of 1.2 µM. It demonstrates moderate oral bioavailability in rat models (F=14%), supporting its use in antiviral research for hepatitis C drug discovery.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1019639-20-3
MW282.26
FormulaC10H14N6O4
SMILESN(=[N+]=[N-])[C@]1(CO)O[C@H]([C@@H](C)[C@@H]1O)N2C(=O)N=C(N)C=C2
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information