TM5441 sodium

• Catalog Number: orb2283351
• Category: Small Molecules
• Description: TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].
• Purity: 98.00%
• MW: 450.8
• Biological Activity: TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].
• CAS Number: [2319722-53-5]
• Formula: C₂₁H₁₆ClN₂NaO₆
• SMILES: N(C(COCC(NC1=C(C(O)=O)C=C(Cl)C=C1)=O)=O)C=2C=C(C=CC2)C=3C=COC3.[Na]
• Storage: -20°C
• Note: For research use only