TM-1

SKU: orb1687030

Description

TM-1 is a cell-permeable PDHK inhibitor with IC50 values of 2.97 µM and 5.2 µM against PDHK1 and PDHK2, respectively. It activates the pyruvate dehydrogenase complex by blocking its phosphorylation and has been shown to suppress cancer cell proliferation in vitro, making it a useful tool for studying cancer metabolism.

Research Area

Cell Biology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 921099-13-0
• MW: 468.54
• Purity: 99.61% (May vary between batches)
• Formula: C₂₆H₃₂N₂O₆
• SMILES: O=C1OC2=CC(OCCN3CCN(CCO)CC3)=CC=C2C(=C1C=4C=CC(OC)=C(OC)C4)C
• Target: Autophagy,Proteasome

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16424570