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TLX agonist 3

SKU: orb3174959

Description

TLX agonist 3 is a potent and selective tailless homolog (TLX, NR2E1) agonist, with an EC50 of 0.25 μM and a Kd of 1.6 μM. It exhibits high selectivity for related nuclear receptors and enhances TLX oligomerization (EC50 = 5.0 μM). TLX agonist 3 is applicable in research on neurodegenerative diseases.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3032232-47-3
MW468.48
FormulaC25H23F3N4O2
SMILESO=C(NC=1C=C(C=C(C1)C(F)(F)F)N2C=NC(=C2)C)C=3C=C(N=C4C=CC=CC43)OCCCC
TargetOrphan Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information