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TLR7/8 agonist 9
Catalog Number: orb1944361
| Catalog Number | orb1944361 |
|---|---|
| Category | Small Molecules |
| Description | TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research [1]. |
| Purity | 98.00% |
| MW | 366.46 |
| Biological Activity | TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments. This compound is utilized in cancer immunotherapy research [1]. |
| CAS Number | 2649170-17-0 |
| Formula | C20H26N6O |
| SMILES | N(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1 |
| Storage | -20°C |
| Note | For research use only |
TLR7/8 agonist 1 dihydrochloride [orb1220903]
> 98% (HPLC)
1620278-72-9
432.4
C22H27Cl2N5
500 mg, 200 mg, 50 mg, 100 mg, 10 mg, 25 mg, 5 mg, 1 gTLR7/8 agonist 1 dihydrochloride [orb1301691]
98.33%
[1620278-72-9]
432.39
C22H27Cl2N5
100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 1 mg, 1 ml x 10 mM (in DMSO)TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride [orb1984564]
98.00%
2388520-36-1
873.48
C41H69ClN6O12
500 mg, 100 mg
