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TLR7/8 agonist 14

SKU: orb3174402

Description

TLR7/8 agonist 14 is a dual-target agonist of TLR7 and TLR8, with EC50 values of 75 μM for TLR7 and 96 μM for TLR8. This compound enhances the secretion of pro-inflammatory cytokines TNF-α, IL-1β, IL-8, and IFN-γ, while also increasing cytokine secretion and CD86 expression levels. TLR7/8 agonist 14 is applicable in colorectal cancer research.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

TargetIFNAR,Interleukin,TNF,TLR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information