TLQP-62 (mouse,rat)

SKU: orb3142735

Description

TLQP-62 (mouse, rat) is a secreted C-terminal peptide derived from the protein VGF. It activates the BDNF-TrkB signaling pathway, inducing acute and transient phosphorylation of TrkB receptors and downstream phosphorylation of CREB(Ser133). TLQP-62 effectively enhances long-term fear memory formation in wild-type mice and can reverse memory deficits in VGF heterozygous knockout mice. This compound is useful for researching memory-related neurological diseases, such as Alzheimer's disease and frontotemporal dementia.

Key Properties

• Target: Endogenous Metabolite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Endogenous Metabolite