TL8-506

SKU: orb1689059

Description

TL8-506 is a potent and selective TLR8 agonist that triggers robust cytokine and chemokine release. This activity underpins its utility in immunological research, where it is applied in both in vitro cellular assays and in vivo models to study inflammation and potential therapeutic interventions for autoimmune conditions.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 1268163-15-0
• MW: 331.37
• Purity: 99.97% (May vary between batches)
• Formula: C₂₀H₁₇N₃O₂
• SMILES: N#CC1=CC=CC(=C1)C2=CC=C3C=C(C(=O)OCC)CC(=NC3=C2)N
• Target: TLR,Interleukin,Antibacterial
• Solubility: DMSO:10 mg/mL (30.18 mM)

Bioactivity

• Target IC50:
  TLR8:30 nM (EC50)
• In Vitro:
  TL8-506 is a highly selective TLR8 agonist with a half-maximal effective concentration (EC50) of 30 nM.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TL8506

Compound Identifiers

PubChem CID

51033962