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TK-684

SKU: orb3135662

Description

TK-684 is a potent and selective allosteric inhibitor of SHP2, with IC50 values of 2.1 nM for SHP2WT and greater than 1000 nM for SHP2PTP. It inhibits cell proliferation and induces apoptosis (apoptosis). Additionally, TK-684 reduces the protein expression of p-AKT and p-ERK.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

TargetApoptosis,Phosphatase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information