Tizanidine hydrochloride

SKU: orb1310753

Description

Tizanidine HCl is a centrally-acting α2-adrenergic agonist that suppresses neurotransmitter release from noradrenergic neurons. It is widely used in research to study muscle spasticity mechanisms and to probe adrenergic signaling pathways in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 64461-82-1
• MW: 290.17
• Purity: 99.96% (May vary between batches)
• Formula: C₉H₉Cl₂N₅S
• SMILES: Cl.Clc1c(NC2=NCCN2)c2nsnc2cc1
• Target: Apoptosis,Wnt/beta-catenin,Akt,Adrenergic Receptor
• Solubility: H2O:29 mg/mL (99.94 mM);DMSO:45 mg/mL (155.08 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.23 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AdrenergicReceptor, Adrenergic Receptor, Beta Receptor, DS 103-282, inhibit, Inhibitor, Tizanidine, Tizanidine HCl, Tizanidine hydrochloride, Tizanidine Hydrochloride, α2 adrenergic receptor

Compound Identifiers

PubChem CID

114869