TIPARP-IN-1

SKU: orb3174944

Description

TIPARP-IN-1 (Compound 15) is a selective inhibitor of PARP7 (TIPARP, also known as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inducible PARP) with an IC50 value of 2.15 nM. By inhibiting TIPARP, TIPARP-IN-1 can restore the IFN signaling pathway in tumors. In the tumor microenvironment, it selectively activates anti-tumor immune responses while avoiding the systemic production of cytokines. TIPARP-IN-1 is applicable for research in head and neck squamous cell carcinoma.

Key Properties

• CAS Number: 3106183-96-1
• MW: 503.45
• Formula: C₂₂H₂₃F₆N₅O₂
• SMILES: C(=O)([C@H]1C[C@@H](CC=2C=C(C(F)(F)F)C(=O)NC2)C1)N3C[C@@H](C)N(CC3)C=4N=CC(C(F)(F)F)=CN4
• Target: IFNAR,PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IFNAR,PARP