Tiomolibdate diammonium

SKU: orb1940589

Description

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.

Images & Validation

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Key Properties

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CAS Number	15060-55-6
MW	260.27
Purity	>98% (HPLC)
Formula	H₈MoN₂S₄
SMILES	[NH4+].[NH4+].[S-][Mo]([S-])(=S)=S
Target	Apoptosis\| ERK1\| ERK2
Solubility	In Vitro: DMSO : 5 mg/mL (19.21 mM)

Bioactivity

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In Vivo	Ammonium tetrathiomolybdate(VI) (ATTM) (i. v. ; 10 mg/kg) confers significant neuroprotection. Animal model: Wistar Rats. Dosage: 10 mg/kg. Administration: Intravenous. Result: Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644

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Gene Symbol

Apoptosis| ERK1| ERK2

Protocol Information

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Purity:	98.00% (May vary between batches)
CAS Number:	15060-55-6
MW:	260.28
Formula:	H₈MoN₂S₄