Tiomolibdate diammonium

SKU: orb1940589

Description

Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.

Key Properties

• CAS Number: 15060-55-6
• MW: 260.27
• Purity: >98% (HPLC)
• Formula: H₈MoN₂S₄
• SMILES: [NH4+].[NH4+].[S-][Mo]([S-])(=S)=S
• Target: Apoptosis| ERK1| ERK2
• Solubility: In Vitro: DMSO : 5 mg/mL (19.21 mM)

Bioactivity

• In Vivo:
  Ammonium tetrathiomolybdate(VI) (ATTM) (i. v. ; 10 mg/kg) confers significant neuroprotection. Animal model: Wistar Rats. Dosage: 10 mg/kg. Administration: Intravenous. Result: Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ammonium molybdenum sulfide | Ammonium tetrathiomolybdate | ATTM | Coprexa | NSC 286644

Quick Database Links

Gene Symbol

Apoptosis| ERK1| ERK2