TINK-IN-1

SKU: orb1944752

Description

TINK-IN-1 is a potent and selective TNIK inhibitor with an IC50 of 8 nM. It has been shown to suppress colorectal cancer cell viability in vitro and serves as a valuable chemical probe for investigating related biological pathways in cancer and neurodevelopmental research.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1417795-25-5
• MW: 416.47
• Purity: 99.80% (May vary between batches)
• Formula: C₂₄H₂₄N₄O₃
• SMILES: N#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C(OC)=C3)N4CCOCC4
• Target: Wnt/beta-catenin,Others,MAPK

Bioactivity

• Target IC50:
  TNIK:8 nM|ERG (human):4.7 μM|β-lactamase:6.3 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

betacatenin, beta-catenin, bcatenin, βcatenin, TNIK, Wnt/b-catenin, Wnt/betacatenin, Wnt, Wnt/β-catenin, TINKIN1

Compound Identifiers

PubChem CID

71540729