TIM-3-IN-2

SKU: orb2278000

Description

TIM-3-IN-2 is a small molecule inhibitor that blocks TIM-3 interactions with its ligands PtdSer, CEACAM1, and Galectin-9. It reverses TIM-3-mediated immunosuppression and cytokine production, making it a valuable tool for investigating TIM-3 function in cancer immunology and autoimmune disease models, both in vitro and in vivo.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 1113126-49-0
• MW: 461.47
• Purity: 98.93% (May vary between batches)
• Formula: C₂₅H₂₃N₃O₆
• SMILES: O=C(NC1=CC=C(OC)C=C1OC)COC2=CC=CC(=C2)C3=NC(=NO3)C=4C=CC(OC)=CC4
• Target: Immunology/Inflammation related
• Solubility: DMSO:80 mg/mL (173.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inflammation related, Inflammationrelated, Immunology related, Immunologyrelated, TIM-3

Compound Identifiers

PubChem CID

46266591