TIM-063

SKU: orb1744164

Description

TIM-063 is a potent, cell-permeable CaMKK inhibitor that acts by competing with ATP at the kinase's catalytic domain. It shows high selectivity with K(i) values of 0.35 µM for CaMKKα and 0.2 µM for CaMKKβ. This tool compound is widely used in vitro to study AMPK and calcium signaling pathways in metabolic and neurological research.

Research Area

Neuroscience

Key Properties

• CAS Number: 2493978-38-2
• MW: 331.28
• Formula: C₁₈H₉N₃O₄
• SMILES: N(=O)(=O)C1=C2C3=C(C=4N(C(=O)C3=CC=C2)C=5C(N4)=CC=CC5)C=C1O
• Target: CaMK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642637