TIE-2/VEGFR-2 kinase-IN-4

SKU: orb2277616

Description

TIE-2/VEGFR-2 kinase-IN-4 is a potent benzimidazole-based dual inhibitor of TIE-2 and VEGFR-2 tyrosine kinases, with IC50 values of 5.2 nM and 5.1 nM, respectively. It is a valuable research tool for studying angiogenesis and related pathways in both cellular and animal models of cancer and vascular diseases.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 433224-29-4
• MW: 539.44
• Formula: C₂₆H₁₇F₄N₅O₄
• SMILES: N(C(=O)C1=CC=CO1)C=2NC=3C(N2)=CC=C(OC4=CC=C(NC(NC5=CC(C(F)(F)F)=CC=C5F)=O)C=C4)C3
• Target: Tie-2,Others,VEGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10230568