TIE-2/VEGFR-2 kinase-IN-4

• Catalog Number: orb2277616
• Category: Small Molecules
• Description: TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, is a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, with IC50 values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1].
• CAS Number: 433224-29-4
• Purity: 98.00%
• MW: 539.44
• SMILES: N(C(=O)C1=CC=CO1)C=2NC=3C(N2)=CC=C(OC4=CC=C(NC(NC5=CC(C(F)(F)F)=CC=C5F)=O)C=C4)C3
• Formula: C₂₆H₁₇F₄N₅O₄
• Biological Activity: TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting inhibitory concentration (IC50) values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.