TIC10g

SKU: orb2646308

Description

TIC10g is a dual TLR7 and TLR9 inhibitor that suppresses TNF-α release in mouse macrophages and human B cells. It blocks NF-κB and MAPK activation, demonstrating anti-inflammatory potential for research in autoimmune diseases like lupus and rheumatoid arthritis.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 754998-88-4
• MW: 367.4
• Formula: C₂₀H₂₁N₃O₄
• SMILES: N=1C=C(C=2C=CC=3OCOC3C2)N(C1NCC4=CC=C(OC)C=C4OC)C
• Target: TLR,p38 MAPK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1096525