Tiazofurin

SKU: orb1303201

Description

Tiazofurin (NSC-286193) is a synthetic nucleoside analog with antineoplastic properties. It functions as a prodrug, being metabolized intracellularly to TAD, a potent inhibitor of IMP dehydrogenase (IMPDH). This mechanism has been investigated in vitro and in vivo for its effects on cancer cell proliferation and tumor growth.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 60084-10-8
• MW: 260.27
• Purity: 99.28% (May vary between batches)
• Formula: C₉H₁₂N₂O₅S
• SMILES: NC(=O)c1csc(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
• Target: Dehydrogenase
• Solubility: DMSO:50 mg/mL (192.11 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, NSC 286193, IMPDH, NSC286193, NSC-286193, Orthopoxvirus, Nucleoside Antimetabolite/Analog, Inhibitor, Riboxamide, Tiazofurin

Compound Identifiers

PubChem CID

457954