THZ1-R

SKU: orb1708362

Description

THZ1-R is a non-covalent, reversible analog of the CDK7 inhibitor THZ1, lacking its covalent-binding acrylamide group. This results in reduced inhibitory potency against CDK7. It serves as a key chemical tool for studying CDK7-dependent transcription and cell cycle processes in cancer research models, both in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 1621523-07-6
• MW: 568.07
• Formula: C₃₁H₃₀ClN₇O₂
• SMILES: O=C(NC=1C=CC=C(C1)NC=2N=CC(Cl)=C(N2)C3=CNC=4C=CC=CC43)C5=CC=C(C=C5)NC(=O)CCCN(C)C
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

119081415