THZ1 Hydrochloride

• Catalog Number: orb1744860
• Category: Small Molecules
• Description: THZ1 Hydrochloride is a potent, selective covalent inhibitor of CDK7, exhibiting an IC50 value of 3.2 nM. It also targets closely related kinases CDK12 and CDK13, leading to the downregulation of MYC expression.
• Purity: 98.00%
• MW: 602.51
• SMILES: CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl.Cl
• Formula: C₃₁H₂₉Cl₂N₇O₂
• Biological Activity: THZ1 Hydrochloride is a potent, selective covalent inhibitor of CDK7, exhibiting an IC50 value of 3.2 nM. It also targets closely related kinases CDK12 and CDK13, leading to the downregulation of MYC expression.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.