Thrombin Receptor Agonist peptide

• Catalog Number: orb216831
• Category: Proteins
• Description: Thrombin Receptor Agonist peptide
• Form/Appearance: Lyophilized powder
• Purity: > 95%
• Protein Sequence: H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH
• MW: 1739.96
• Application notes: Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.
• Source: Synthetic
• CAS Number: 137339-65-2
• Formula: C₈₁H₁₁₈N₂₀O₂₃
• Storage: Shipped at 4°C. Store at -20°C for one year.
• Alternative names: Thrombin Receptor Activator Peptide 14, PAR-1 (1-1
• Note: For research use only