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Catalog Number | orb216831 |
---|---|
Category | Proteins |
Description | Thrombin Receptor Agonist peptide |
CAS Number | 137339-65-2 |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
MW | 1739.96 |
Formula | C81H118N20O23 |
Protein Sequence | H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH |
Source | Synthetic |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Alternative names | Thrombin Receptor Activator Peptide 14, PAR-1 (1-1 Read more... |
Note | For research use only |
Application notes | Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation. |
Expiration Date | 12 months from date of receipt. |
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