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THR-123

SKU: orb3180391

Description

THR-123 is an orally active ALK3 peptide agonist. It binds relatively weakly to ALK2 and does not bind to ALK6. THR-123 can inhibit inflammation, apoptosis (cell death), and epithelial-mesenchymal transition, as well as reverse fibrosis already formed in five different acute and chronic kidney injury mouse models. THR-123 is applicable for research on renal fibrosis.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetInterleukin,Integrin,Cadherin,TGF-beta/Smad,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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