THK01

SKU: orb1982601

Description

THK01 is a potent and selective ROCK2 inhibitor (IC50 = 5.7 nM vs. ROCK2; 923 nM vs. ROCK1). It blocks the ROCK2-STAT3 signaling pathway, effectively inhibiting breast cancer metastasis in research models, making it a valuable tool for studying cancer biology and metastasis in vitro and in vivo.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2226941-26-8
• MW: 327.34
• Formula: C₂₀H₁₃N₃O₂
• SMILES: O=C1C2=C3C(=C4C(=C2CN1)C=5C(N4)=CC=CC5)NC=6C3=CC(O)=CC6
• Target: ROCK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139589939