Thioredoxin Reductase 1 Antibody

• Catalog Number: orb1731229
• Category: Antibodies
• Description: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IHC, IP, WB
• Reactivity: Human, Mouse
• Isotype: Rabbit IgG
• Immunogen: Recombinant protein of human TXNRD1
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 71 kDa; Observed MW: 55 kDa
• Entrez: 7296
• UniProt ID: Q16881
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: TR; TR1; TXNR; TRXR1; GRIM-12
• Note: For research use only
• Expiration Date: 12 months from date of receipt.