Thiocolchicoside

SKU: orb1304668

Description

Thiocolchicoside is a synthetic muscle relaxant with analgesic properties that functions as a competitive antagonist at GABAA and glycine receptors. Its potent convulsant activity necessitates caution in seizure research. It is utilized in neuropharmacological studies to investigate receptor mechanisms and muscle relaxation in experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 602-41-5
• MW: 563.62
• Purity: 99.94%
• Formula: C₂₇H₃₃NO₁₀S
• SMILES: COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c1OC
• Target: GABA Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM);H2O:177.4 mM;DMSO:55 mg/mL (97.58 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Coltramyl, central, acid, anti-inflammatory, analgesic, nervous, inhibit, muscle, GABA Receptor, glycine, GABAA, GABAReceptor, Gamma-aminobutyric acid Receptor, Inhibitor, Thiocolchicine 2-glucoside analog, Thiocolchicoside, relaxant, system, γ-Aminobutyric acid Receptor, γ-aminobutyric

Compound Identifiers

PubChem CID

9915886