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Catalog Number | orb1980125 |
---|---|
Category | Small Molecules |
Description | Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cofactors. |
Purity | 98.00% |
MW | 679.49 |
Biological Activity | Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cofactors. |
CAS Number | 4090-29-3 |
Formula | C21H27N7O13P2S |
SMILES | NC(=S)C1CCCN(C1)C1OC(COP(O)(=O)OP(O)(=O)OCC2OC(C(O)C2O)n2cnc3c(N)ncnc23)C(O)C1O |
Storage | -20°C |
Note | For research use only |